Synthesis of a Series of α, β-Unsaturated Ketoximes and their Corresponding Acetate Esters

A series of 1,3-diarylprop-2-en-1-one oximes (7-12) were synthesized via reaction (1-6) with NH2OH. HCl in dry pyridine. In order to produce the required products (13-18) as anti-isomers, these (7–12) then treated acetic anhydride Different substitutes are maintained, resulting separation different yields The recently produced esters thought be useful building blocks for synthesis substituted pyridines and many other nitrogen-holding complexes, which elaborate structures medicinal chemistry present a variety pharmaceutical medications. characterized their structural details clarified using 1H NMR spectroscopy representative one sample ester oxime, (FT-IR, UV) investigations, melting point analysis. Besides elemental micro analysis (C, H, N) same samples, suggested mechanisms reactions investigated according calculations.